We are here in a very fertilizer ecosystem

OUR CORRESPONDENT IN STRASBOURG.

Nothing is predestined Pascal Neuville team, less than two years after the creation of the company to join Strasbourg and its biotechnology centre of Illkirch. This PhD in molecular biology was educated in Alsace, worked for three years in transgene in Strasbourg, but he then left the Rhenish city to lead a laboratory at the Faculty of Geneva before joining the CNRS and professors Maurice Israel and Pierre Potier, the founders of the company. "Our goal, says, was to discover new treatments for diseases of the brain, and neurodegenerative disorders including Alzheimer's, and this testing molecules already on the market, but used for other types of treatment.".

In 2001, Pascal Neuville was the first employee of the structure of Gif-sur-Yvette. But soon, a dozen engineers and researchers had joined him. "After 15 months of incubation in the premises of the CNRS, we needed to move." At the same time, it sought to enlarge Faust Pharmaceuticals by buying a company additional expertise. "It is by visiting a umpteenth Park of innovation of Illkirch, he found his prey. In case Euroclide, who was working on a new class of drugs to the variable and programmed effects depending on the needs. "It has immediately been seduced by the richness of the environment in the life sciences."

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The proximity of Basel, co-leaders of the pharmaceutical industry, but also of the University of Strasbourg with Nobel Prize winner Jean-Marie Lehn and Pierre Chambon laboratories also played for the relocation to the shore Rhenish. "Except a Secretary, any research team followed, many are still with us, others are now working in neighboring laboratories, on the same pole of innovation. We are here in a very fertilizer ecosystem. "And Faust, renamed in 2009 Domain Therapeutics, tirelessly continues its work to the rhythm of successive fundraising: Sofinnova, Auriga, AGF, Siparex Ventures, the Edmond de Rothschild financial...

Thus more than 10 million euros was invested in the clinical development of a drug for patients with Parkinson's. But, in 2008, between the clinical phases 2 and 3, it was stopped due to potential risk of long-term toxicity. Result, had to reduce the sail, go from 35 to 15 researchers. "But we have saved the agreement we had with the Japanese Takeda to work on the Euroclide platform." Since then, the company has research contracts with industry from around the world, history of the costs of operation of the society. Research, however, remains fully funded by venture capital funds.

But polls by experience, Domain will back its next discoveries to the pharmaceutical industry before the phases of clinical development. In this regard, Domain has to be labeled by the pole of competitiveness Alsace Biovalley Athos (budget EUR 5.1 million) project conducted with its neighbours on the pole, Prestwick Chemical and the Institute of genetics and molecular and cellular biology. It comes to new therapies for diseases of the central nervous system, including schizophrenia. "From here in October, we will give a first product in this family, which will allow to harvest a coup several years of sales," welcomes already Pascal Neuville. Illkirch, this scientist is not far from having found the paradise of biotech, him who led with passion, three years after the Professor Jacques Marescaux, the pole of competitiveness Alsace Biovalley. Next goal by 2012: make scoring Domain in stock, on Alternext.

Photo credits: Dr. Pascal Neuville does not regret his diving in the Alscace Biovalley environment, interconnected to the Switzerland and the Germany. 020692387627web 020692699882web